Pressure drop characteristics of a gasketed commercial plate heat exchanger configured for single-phase water-to-water flow application are presented. Isothermal pressure drop data are provided for two symmetric 30 degrees/30 degrees, 60 degrees/60 degrees and a nonsymmetric 30 degrees/60 degrees (mixed) chevron plate configuration in the plate heat exchanger. Reynolds number was varied from 500 to 2,500. The experimental data are found to be a strong function of chevron angle and Reynolds number. Experimental results show that mixed plate configuration can be a choice in optimizing the plate heat exchanger design for improved performance. Based on experimental data, correlations are presented for estimation of friction factor.