The sensitivity of titanium to increasing oxygen content and the high cost of reducing oxygen content in titanium have prevented its broader applications. Here we report a low-temperature de-oxygenation process, which can remove oxygen from titanium powders to less than 1000 ppm from original oxygen levels of over 20,000 ppm. The effect of molten salt on de-oxygenation was investigated in this study. The calcium halide-bearing molten salt facilitates the dissolution of solid calcium and creates a metal-molten solution condition by forming intermediate Ca+ ions and finally Ca2+ ions and electrons (e (-)). The molten salt enables the de-oxygenation of Ti at temperatures lower than the melting point of calcium. It will be shown that the de-oxygenation temperature can be as low as 873 K (600 A degrees C).