La-doped ZnWO4 nanospheres were successfully synthesized by a hydrothermal synthesis method and further investigated by X-ray diffraction (XRD), scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDS). A novel electrochemical sensor has been fabricated by carbon paste electrode (CPE) coated with the prepared La-doped ZnWO4 nanospheres. Electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV) and differential pulse voltammetry (DPV) were applied to characterize the electrochemical properties of the sensor. By using DPV method, low detection limits of DA and UA were obtained to be 0.04 mu mol . L-1 and 0.03 mu mol . L-1 (S/N = 3), with the linear calibration curves over the concentration ranges of 0.10 similar to 43.03 mu mol . L-1 and 0.08 similar to 106.65 mu mol . L-1, respectively. Furthermore, the sensor was employed to detect DA and UA with good selectivity and sensitivity, and the interference experiment as well as the practical sample analysis was also well performed. (C) 2016 The Electrochemical Society. All rights reserved.