Novel thiophenyl-substituted anthracene derivatives (D-A)bearing a variety of electron-withdrawing groups were designed and synthesized for organic solar cells (OSCs). Their electrochemical and electro-optical properties were examined with strong donor-acceptor interaction. The electrochemical properties were examined by cyclic voltammetry (CV) measurements. These estimated values from CV measurements are in good agreement with the optical band gaps. HOMO, LUMO, and Eg values of designed organic materials were estimated. Furthermore, these new generation organic materials were fabricated to find their solar cell performances.