A numerical method is demonstrated in which a simple flame temperature criterion of 2700 K is used to map out flammability diagrams as a function of total mixture pressure and equivalence ratio in the hypergolic system, MMH/NTO/He. The computed results are in good agreement with experimentally determined ignition diagrams for MMH/NTO/He. The method is used to predict the lower and upper hypergolicity limits of other mixtures known to be hypergolic at 298 K and 1 atm. Comparisons between available experimental data (mixing ratios) and calculated limits lead to the conclusion that the present numerical method may allow the screening of other fuel/oxidant systems potentially of interest for spacecraft propulsion as well as for the determination of the range of mixing ratios able to ensure autoignitibility (hypergolicity) in combustion devices. In the safety field, the same method allows for the rapid assessment of hazards in terms of hypergolicity. (C) 2016 Published by Elsevier Inc. on behalf of The Combustion Institute.