This study assessed the effect of experimental silane primers and two adhesive resin cements on resin zirconia adhesion strength. The surfaces of cut Y-TZP zirconia blocks (Lava (TM) Frame), 16 mm x 16 mm x 4.5 mm, were pretreated twice. First, they were grit-blasted with Korox (TM) alumina powder (110 mu m) followed by silica-coating with Rocatec (TM) Soft. Next, the blocks were randomly assigned into eighteen sub-groups (n = 6, N = 108) according to three primers (control ESPE Sil (TM), 1.0 vol.-% 3- acryloxypropyltrimethoxysilane, and 1.0 vol.-% 3- acryloxypropyltrimethoxysilane + 0.5 vol.-% bis-12( triethoxysilyl) ethane), two in dentistry used resin cement products (Multilink (TM) Speed, and Multilink (TM) N), and three storage conditions (24 h dry, 1 month immersed in distilled water, and 6 months immersed in distilled water at room temperature) used. Onto each pretreated zirconia block, four cylindrical resin composite cement stubs were prepared and light-cured. The surface roughness, contact angle, and adhesion (shear bond) strength (SBS) were measured, and statistically analyzed (ANOVA, the Tukey's test, p < 0.05). No statistical differences were observed in surface roughness values of different primer-treated zirconia groups. After six months of water aging, the shear bond strength of the groups that employed 1.0 vol.-% 3- acryloxypropyltrimethoxysilane (9.0 MPa +/- 0.8 MPa), and the blend of 1 vol.-% 3- acryloxypropyltrimethoxysilane + 0.5 vol.-% bis-12-( triethoxysilyl) ethane (8.9 MPa +/- 2.0 MPa) with Multilink (TM) Speed resin composite cement were statistically insignificantly higher compared to using ESPE Sil (TM) (8.7 MPa +/- 1.8 MPa). The experimental primers may have potential to be used for long-term resin zirconia adhesion.