Purification of Chinese herbal extract with chitosan hydrochloride: Flocculation of single impurity and flocculation mechanism

Xiaojiao An; Yong Kang; Li Qin; Yajing Tian; Guishui Li

Korean Journal of Chemical Engineering, Vol.34, No.6, 1756-1762, June, 2017

DOI10.1007/s11814-017-0055-8 Export Citation

Purification of Chinese herbal extract with chitosan hydrochloride: Flocculation of single impurity and flocculation mechanism

Xiaojiao An, Yong Kang^†, Li Qin, Yajing Tian, and Guishui Li¹

School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China
¹College of Mechanical Engineering, Tianjin University of Science and Technology, Tianjin 300222, China

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Chitosan hydrochloride (CHC) was used for flocculation of impurities (tannin and protein) in Ma-xinggan-shi solution (MSS), which is a Chinese herbal medicine solution (CHMS). To study the flocculation mechanism, simulated solutions of pure tannin and pure protein in water flocculated by CHC were investigated. For MSS flocculation by CHC, flocculation performance was assessed in terms of suspended turbidity, impurities removal rate as well as active components retention rate. CHC showed high capability of maintaining a low turbidity over a wide range of the polymer dosage. The optimum dosage of CHC was 0.6 g/L in base of different solution turbidity, and it also demonstrated the retention rate of total soluble polysaccharide (TSP) and ephedrine reached 78.4% and 92%, respectively.

Keywords:Chitosan Hydrochloride;Chinese Herbal Medicine Solution;Flocculation Mechanism;Tannin;Protein

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