MoS2 Quantum dots-interspersed Bi2WO6 heterostructure is fabricated for photocatalytic applications for the first time. It exhibits enhanced visible light-driven photocatalytic detoxification and disinfection in wastewater compared to bare Bi2WO6 and MoS2. MOS2 quantum dots as a co-catalyst applied in photo catalysis oxidation possesses multiple merits: (1) noble-metal-free; (2) high mobility of photogenerated charge carriers; (3) high adsorption capacity and (4) improved capture capacity of visible light photons. Electron-hole separation rate which is critical for an efficient photocatalysis is greatly improved via the built-in electric field of p-n heterostructure and the quantum dots interspersed on the surface. This work shed a light on loading MoS2 quantum dots as a co-catalyst on a support aiming to significantly improve its photocatalytic performance in organic pollutants degradation and bacteria inactivation. (C) 2017 Elsevier B.V. All rights reserved.