Deep eutectic solvents (DESs) have been deemed as green solvents due to their similar physical properties to ionic liquids. The most advantage of DESs, especially choline chloride-based DESs, is that they are biodegradable and non-toxic. In this work, several choline-like DESs are synthetized and characterized by H-1 NMR, FTIR, UV-vis, Raman and ESI-MS. The DESs with different straight alkyl chains linked to N atom were studied. It is found that [C(12)DMEA]Cl/FeCl3 shows the best performance and 52.9% of desulfurization efficiency is obtained. For comparison, two kinds of phenyl substituted DESs, [BzMDEA]Cl/FeCl3 and [BzMDEA]Cl/FeCl3, are employed to investigate the extractive mechanism. The result shows that CH-pi interaction may be much stronger than pi-pi interaction in this reseasch. The DESs can be regenerated by water and the extractive efficiency is almost not declined. (C) 2017 Elsevier B.V. All rights reserved.