The destruction of toluene in dielectric barrier discharge (DBD) reactor coupled with a series of CeO2-MnOx catalysts was investigated in this work. All catalysts prepared by sol-gel method were characterized in detail using N-2 adsorption, XRD, TEM, H-2-TPR, Raman, O-2-TPD and XPS analysis technology. The effect of input power, molar ratio of Ce/Mn, gas flow rate and initial concentration of toluene on the removal efficiency of toluene and CO2 selectivity has been investigated. The plasma catalytic system improves the removal efficiency and CO2 selectivity significantly compared with the plasma alone system. The catalytic performance of CeO2-MnOx catalysts are higher than pure CeO2 and MnOx, which might be contributed to the synergistic effect between CeO2 and MnOx (such as Mn3+/Mn2+ and Ce4+/Ce3+ redox couples) in the CeO2-MnOx catalysts. The highest removal efficiency of toluene (95.94%) and CO2 selectivity (90.73%) are acquired with Ce1Mn1 catalyst. The reason may be that: (1) the increased BET specific surface area and the decreased grain size can be obtained from CeO2-MnOx catalyst. (2) The formation of CeO2-MnOx solid solution resulted from the incorporation of Mn cations into the CeO2 lattice could generate more oxygen vacancies and improve the mobility of oxygen. On the basis of the analytic results of GC/MS, the pathways of toluene destruction in the plasma -catalysis system are discussed. (C) 2017 Elsevier B.V. All rights reserved.