Highly efficient persulfate oxidation process activated with pre-magnetization Fe-0 (pre-magnetization Fe-0/PS) was employed to degrade Orange anthraquinone dye at different Fe-0 dosages (1-8 mmol/L), initial pH levels (3-10) and PS dosages (2-8 mmol/L). Pre-magnetization Fe-0/PS possessed 8.4-119.6 folds enhancement in degradation rate and could widen pH range and save 90% Fe-0 and PS dosage when compared with conventional Fev/PS process. And this effect was ascribed to the change of Fe-0 characteristics after pre-magnetization. This significant improvement was also observed on the degradation of many refractory contaminants of tartrazine, phenol, 2,4-dichlorophenol (2,4-DCP), p-chlorophenol, chlorobenzene, nitrobenzene, p-nitrophenol and p-nitrchlorobenzene, which were 2.8-11.4 folds of those by Fe-0/PS process. Pre-magnetization Fe-0/PS is a more promising process since it does not require any change of the present water and wastewater treatment process, and does not need an extra energy source, costly materials, and complex equipment. (C) 2016 Elsevier B.V. All rights reserved.