A novel superoleophilic sponge, which has been prepared by a simple sol-gel process using microcrystalline cellulose (MCC) and methyl cellulose (MC), and its oil/water separation apparatus application are presented here. The samples were characterized by Scanning Electron Microscopy (SEM), X-ray diffraction (XRD), Fourier Transform Infrared Spectra (FTIR), and so on. The results indicated that MCC/MC silica sponge (MCC-CH3) had been successfully introduced C = O and methyl groups and exhibits better mechanical properties, absorption capacity, and high oil selectivity. Besides, a novel oilwater separation apparatus was designed to make MCC-CH3 a further practical application. Based on this simple but flexible and intelligent design, oil collection, sorption materials regeneration, and free navigation can be simultaneously achieved in the remediation of oil spills. The results showed the discharge flow of n-hexane was about 11700 g.h(-1.)g(-1), and the oil ratio of the discharge mixture reached 99% under a continuous operation.