The rapid growth of vehicular pollution; mostly running on the diesel engine, emissions emerging are the concerns of the day. Owing to clean burn characteristics features, Hydrogen (H-2) as a fuel is the paradigm of the researcher. Extensive research presented in the literature on H-2 dual fueled diesel engine reveals, the significant role of H-2 in reducing emissions and enhancing the performance of a dual fueled diesel engine. With meager qualitative experiment data, the feasibility to develop an efficient Artificial Neural Network (ANN) model is investigated, the developed model can be utilized as a tool to investigate the H-2 dual fueled diesel engine further. In the process of developing an ANN model, engine load and H-2 flow rate are varied to register performance and emission characteristics. The creditability of the experiment is ascertained with uncertainty analysis of measurable and computed parameters. Leave-out-one method is adopted with 16 data sets; seven training algorithms are explored with eight transfer function combinations to evolve a competent ANN model. The efficacy of the developed model is adjudged with standard benchmark statistic indices. ANN model trained with Broyden, Fletcher, Goldfarb, & Shanno (BFGS) quasi-Newton backpropagation (trainbfg) stand out the best among other algorithms with regression coefficient ranging between 0.9869 and 0.9996. (C) 2017 Hydrogen Energy Publications LLC. Published by Elsevier Ltd. All rights reserved.