Computational fluid dynamics (CFD) was used to investigate the hydrodynamics of solid-liquid suspension process in a stirred tank with rigid impellers, rigid-flexible impellers and punched rigid-flexible impellers. The effects of impeller type, impeller speed, flexible connection piece length, impeller spacing, particle size, and aperture size/ratio on the mixing quality were investigated. Results showed that the degree of solid-liquid homogeneity increased with an increase in impeller speed. A long flexible connection piece was conductive to solid particles suspension process. The solid particles could not obtain enough momentum to suspend to the upper region of stirred tank with small impeller spacing. Larger particle size resulted in less homogenous distribution of solid particles. The optimum aperture ratio and aperture diameter of punched rigid-flexible impeller were 12% and 8 mm, respectively, for solid particles suspension process. It was found that punched rigid-flexible impeller was more efficient in suspending solid particles compared with rigid impeller and rigid-flexible impeller at the same power consumption. In addition, less impeller power was consumed by punched rigid-flexible impeller compared with rigid impeller and rigid-flexible impeller at the same impeller speed. (C) 2017 The Society of Powder Technology Japan. Published by Elsevier B.V. and The Society of Powder Technology Japan. All rights reserved.