Perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) are persistent organic pollutants in the environment and have serious health risks, including endocrine disrupting properties, immunotoxicity and developmental effects etc. The photochemical degradation has been proven to be a low-cost, efficient and sustainable technology for the removal of PFOX (X = A or S) in water. At present, most of the investigations have been conducted in ultrapure water and at concentrations much higher comparing to those detected in the real wastewaters. Furthermore, there are few studies about the toxicity of treated water. In this paper, the state of knowledge on the photocatalytic degradation of PFOX, including photo-oxidative and photo-reductive degradation, is reviewed comprehensively. Compared with photooxidation, photo-reduction appears to be more suitable for the PFOX removal since it is more favorable for the defluorination of PFOX and further complete mineralization. The effects of key parameters on the photocatalytic degradation and defluorination process of PFOX are commendably accessed, such as light wavelength, photocatalyst concentration, initial PFOX concentration, pH, reaction atmosphere, temperature, and coexisting organic or inorganic matters. The mechanisms of PFOX photodegradation process are also elucidated in detail. This paper will help to deeply understand PFOX decomposition process and put forward better perspectives in the future for researchers who work in this field. (C) 2017 Elsevier B.V. All rights reserved.