Energy efficiency is one of the main pillars of the European energy strategy and it involves all the economic sectors. The present study proposes an analysis of the energy saving opportunities available in the Italian hotel sector, which has a relevant importance in the national context. The paper introduces a comprehensive model of the Italian hotel sector developed in the LEAP (Long-range Energy Alternatives Planning) environment. The first aim is to estimate the baseline of the consumption, then to evaluate the maximum potential energy saving and, finally, to assess the implementation of a realistic energy efficiency scenario. The paper demonstrates that it may be possible to achieve primary energy savings of 1.6 TWh (13%) in 2030 by implementing financially sustainable energy efficiency measures. (C) 2017 Elsevier B.V. All rights reserved.