In this paper a dynamic simulation model and a thermo-econornic analysis of a novel polygeneration system are presented. The system includes photovoltaic/thermal collectors coupled with a solar-assisted heat pump, an adsorption chiller and an electrical energy storage. The modelled plant supplies electrical energy, space heating and cooling and domestic hot water. The produced solar thermal energy is used during the winter to supply the heat pump evaporator, providing the required space heating. In summer, solar thermal energy is used to drive an adsorption chiller providing the required space cooling. All year long, solar thermal energy in excess, with respect to the space heating and cooling demand, is used to produce domestic hot water. The produced electrical energy is self-consumed by both user and system auxiliary equipment and/or supplied to the grid. The system model includes a detailed electrical energy model for user storage and exchange with the grid along with a detailed building model. This study is a continuation of previous works recently presented by the authors. In particular, the present paper focuses on the real electrical demands of several types of users and on the analysis of the comfort of building users. Differently from the works previously published by the authors, the present work bases the calculations on measured electrical demands of real users (fitness center and offices). The system performance is analyzed with two different electricity supply contracts: net metering and simplified purchase/resale arrangement. Daily, weekly and yearly results are presented. Finally, a sensitivity analysis is performed in order to determine the system performance as a function of the system main design/control parameters and to evaluate the minimum Simple Pay Back period. The results outlined a share of the electrical energy storage system on the self-consumed electrical energy of about 20%. The economic profitability is better in case of net metering contract compared to the simplified purchase/resale arrangement one. Moreover, a Simple Pay-Back of about 15 years is achieved for the best configuration, decreasing to 5.6 years in case of capital investment incentive of 65%. The best system configuration, in terms of solar field area, for the fitness center user ranges from 250 to 300 m(2). (C) 2017 Elsevier Ltd. All rights reserved.