The novel, thermally stable explosive 4,4'-((2,4,6-trinitro-1,3-phenylene)bis(oxy))bis(1,3-dinitrobenzene) (Be referred to as ZXC-5 in our laboratory) has been reported. ZXC-5 can be synthesized by a simple synthetic method (The total synthesis of ZXC-5 requires only two steps and the total yield of ZXC-5 is more than 89%) and shows the superior detonation performances (detonation pressure, detonation velocity, sensitivity toward mechanical stimuli, and temperature of decomposition). The structure of ZXC-5 was characterized by multinuclear (H-1, C-13) NMR and mass spectrometry. The structure in the crystalline state was confirmed by low-temperature single-crystal X-ray diffraction. From the calculated standard molar enthalpy of formation and the measured densities, the detonation properties were predicted by using the EXPLO5 V6.01 thermochemical computer code. The sensitivity of ZXC-5 towards impact, electrostatic discharge, and friction were also measured.