Structure of perovskite oxides La1-xSrxScO3-delta (x = 0, 0.04, 0.09) have been studied by X-Ray powder diffraction method. Orthorhombic distortions are found to decrease with increasing of strontium concentration. Water uptake of Sr-doped lanthanum scandates was studied by means of thermogravimetric analysis over the temperature range of 300-950 degrees C in gas mixture with water and oxygen partial pressure of pH(2)O = 0.24 atm and pO(2) = 0.18 atm, respectively. Based on the thermogravimetry data the hydration enthalpy and entropy have been calculated for oxides La1-xSrxScO3-delta (x = 0.04, 0.09). Sc-45 nuclear magnetic resonance (NMR) spectra were taken at T = 300 K and external magnetic field H-0 = 11.7 T. Sc-45 NMR study revealed that local symmetry around scandium ions in lanthanum scandate was affected by the presence of both strontium and protonic defects. Possible reasons of Sc-45 NMR spectra changes have been considered.