Science, Vol.358, No.6360, 234-+, 2017
Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer
Drost Jarno,
van Boxtel Ruben,
Blokzijl Francis,
Mizutani Tomohiro,
Sasaki Nobuo,
Sasselli Valentina,
de Ligt Joep,
Behjati Sam,
Grolleman Judith E.,
van Wezel Tom,
Nik-Zainal Serena,
Kuiper Roland P.,
Cuppen Edwin,
Clevers Hans