화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Journal of Industrial and Engineering Chemistry, Vol.58, 24-32, February, 2018
DOI10.1016/j.jiec.2017.09.002  Export Citation
Electron beam treatment for eliminating the antimicrobial activity of piperacillin in wastewater matrix
László Szabó1, 2, †, Orsolya Gyenes3, Júlia Szabó3, Krisztina Kovács1, András Kovács1, Gabriella Kiskó3, Ágnes Belák3, Csilla Mohácsi-Farkas3, Erzsébet Takács1, 4, and László Wojnárovits1
  • 1Institute for Energy Security and Environmental Safety, Centre for Energy Research, Hungarian Academy of Sciences, Konkoly-Thege Miklós út 29-33, H-1121 Budapest, Hungary
  • 2Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Szent Gellért tér 4, H-1111 Budapest, Hungary
  • 3Department of Microbiology and Biotechnology, Szent István University, Somlói út 14-16, H-1118 Budapest, Hungary
  • 4Faculty of Light Industry and Environmental Engineering, Óbuda University, Doberdó utca 6, H-1034 Budapest, Hungary
E-mail:
Effluents of wastewater treatment plants represent critical control points for antibiotic resistance management. To meet strict regulations coming into effect in the future advanced technologies need to be implemented that can remove the factors contributing to the development of resistance in receiving natural environments. By performing microbiological assays we show that electron beam treatment of a complex synthetic effluent wastewater matrix is able to eliminate one of these factors, the antimicrobial activity of the β-lactam antibiotic piperacillin present at environmentally relevant concentration. Since OH governs the antibacterial inactivation the technology needs to be designed to the stoichiometric presence of OH.
Keywords:Electron beam;Advanced oxidation processes;Antibiotic resistance;Wastewater;Antimicrobial activity
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