화학공학소재연구정보센터
Korean Chemical Engineering Research, Vol.56, No.1, 61-65, February, 2018
고체 산촉매를 이용한 글루코사민으로부터 레불린산 생산
Production of Levulinic Acid from Glucosamine Using Solid Acid Catalyst
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초록
본 연구는 해양 갑각류의 껍질의 주요 구성성분인 키틴/키토산의 단량체인 glucosamine을 고체 산 촉매를 이용하여 화학중간체인 levulinic acid와 5-hydroxymethyl furfural (5-HMF)을 생산하기 위한 전환 반응을 수행하였다. 반응 결과, glucosamine 50 g/L, 반응온도 180 °C, 촉매량 5%, 그리고 반응시간 60분의 조건에서 약 36.86%의 levulinic acid를 얻을 수 있었다. 반면에 5-HMF는 약 0.91%의 낮은 수율로 전환되었다.
In this study, the conversion of glucosamine, which is a major monomer in chitin/chitosan of crustacean shell, using solid acid catalyst was performed to obtain chemical intermediates such as levulinic acid and 5-hydroxymethyl furfural (5-HMF). The conversion reaction was optimized with four reaction factors of selection of ionic resin catalyst, reaction temperature, catalyst amount, and reaction time. As an optimized result, the highest levulinic acid yield was achieved approximately 36.86% under the determined conditions (Amberlyst 15 as a solid-acid catalyst, 180 °C, 5% catalyst amount and 60 min). On the other hand, 5-HMF yield was found to be 0.91% at the condition.
  1. Kamm B, Gruber PR, Kamm M, WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim(2008).
  2. Oh YH, Eom IY, Joo JC, Yu JH, Song BK, Lee SH, Hong SH, Park SJ, Korean J. Chem. Eng., 32(10), 1945 (2015)
  3. Jeong GT, Kim SK, Park DH, Bioresour. Technol., 181, 1 (2015)
  4. Kim DH, Kim AR, Park DH, Jeong GT, Korean Chem. Eng. Res., 54(1), 70 (2016)
  5. Park JH, Kim JS, Korean Chem. Eng. Res., 54(1), 1 (2016)
  6. Jeong GT, Ind. Crop. Prod., 62, 77 (2014)
  7. Lee SB, Jeong GT, Appl. Biochem. Biotechnol., 176(4), 1151 (2015)
  8. Jeong GT, Park DH, Appl. Biochem. Biotechnol., 161(1-8), 41 (2010)
  9. Esmaeili N, Zohuriaan-Mehr MJ, Bouhendi H, Bagheri-Marandi G, Korean J. Chem. Eng., 33(6), 1964 (2016)
  10. Jeong GT, Park DH, KSBB Journal, 26, 341 (2011)
  11. Wang YX, Pedersen CM, Deng TS, Qiao Y, Hou XL, Bioresour. Technol., 143, 384 (2013)
  12. Coh BY, Lee JW, Kim ES, Park YS, J. Chitin Chitosan, 8, 127 (2003)
  13. Kadam ST, Thirupathi P, Kim SS, Tetrahedron, 65, 10383 (2009)
  14. Pal R, Sarkar T, Khasnobis S, ARKIVOC, 570-609(2012).
  15. Tan IS, Lam MK, Lee KT, Carbohydr. Polym., 94, 561 (2013)
  16. Sigma-Aldrich, Product Specification. (Accessed 30 Oct 2014).
  17. Jeon W, Ban C, Kim JE, Woo HC, Kim DH, J. Mol. Catal. A-Chem., 423, 264 (2016)
  18. Son PA, Nishimura S, Ebitani K, Reac. Kinet. Mech. Cat., 106, 185 (2012)
  19. Kim DH, Lee SB, Kim SK, Park DH, Jeong GT, Bioenerg. Res., 9, 1155 (2016)
  20. Rasmussen H, Sørensen HR, Meyer AS, Carbohydr. Res., 385, 45 (2014)
  21. Jeong GT, Ra CH, Hong YK, Kim JK, Kong IS, Kim SK, Park DH, Bioprocess. Biosyst. Eng., 38, 207 (2015)
  22. Chheda JN, Roman-Leshkov Y, Dumesic JA, Green Chem., 9, 342 (2007)