Monodispersed emulsion droplets have promising advantages in food, pharmaceutical, and chemical industries. Previous microchannel emulsification (MCE) plates having the capacity of generating small-sized droplets exhibited very low droplet productivity since these plates operate at a low dispersed-phase flow rate and with a relatively small number of microchannels. An innovative MCE plate with 176176 circular asymmetric through-holes was manufactured, which is comprised of a series of discrete outlets on each microchannel line with an effective cross-sectional area of 1cm(2). The newly fabricated MCE plate is capable to produce monodispersed emulsion droplets with small Sauter mean diameters.