Controllable synthesis of CuCo2S4 was reported for electrochemical sensing of H2O2. It is the first time that CuCo2S4 was explored as electrocatalyst for H2O2 oxidation. A facile hydrothermal approach is developed for the shape-controlled synthesis of CuCo2S4 by just changing the type of metal precursor. The structures, compositions and electrochemical properties of CuCo2S4 were studied. Electrochemical studies showed that flower-like CuCo2S4 with large surface area and three-dimensional porous structure exhibited excellent electrocatalytic activity toward H2O2 oxidation and an excellent analytical performances with a high sensitivity of 857.1 mu A mM(-1)cm(-2), a low detection limit of 0.084 mu M (S/N = 3) and a wide linear range of 4 orders of magnitude were achieved. These results demonstrated that CuCo2S4 was a promising efficient sensing material for electrochemical sensing of H2O2. (C) 2017 Elsevier Ltd. All rights reserved.