Photocatalysts with a hierarchically porous structure have attracted considerable attention owing to their wide pore size distribution and high surface area, which enhance the efficiency of transporting species to active sites. In this study, hierarchically meso-macroporous TiO2 photocatalysts decorated with highly dispersed CdS nanoparticles were synthesized via hydrolysis, followed by a hydrothermal treatment. The textural mesopores and interconnected pore framework provided more accessible active sites and efficient mass transport for the photocatalytic process. The light collection efficiency was enhanced because of multiple scattering of incident light in the macropores. Moreover, the formation of a hetero-junction between the CdS and TiO2 nanoparticles extended the photoresponse of TiO2 to the visible-light range and enhanced the charge separation efficiency. Therefore, the hierarchically meso-macroporous TiO2/CdS photocatalysts exhibited excellent photocatalytic activity for the degradation of rhodaming B under visible-light irradiation. Trapping experiments demonstrated that superoxide radicals (O-center dot(2)-) and hydroxyl radicals (*OH) were the main active species in photocatalysis. A reasonable photocatalytic mechanism of TiO2/CdS heterojunction photocatalysts was also presented. (C) 2017 Elsevier Inc. All rights reserved.