We report on a variety of systems for which it has been possible to measure intrinsic isotope effects on the chemical shielding (the isotope shift) in the solid state. The spin systems investigated are B-11(H-2/1), C-13(H-2/1), N-15(H-2/1), P-31(H-2/1), Mo-95(C-13/12), and Hg-199(C-13/12). Th, results agree well with data available from solution NMR studies.