Road transportation accounts for 25% of total greenhouse gas (GHG) emissions in British Columbia (B.C.) and more than half of these emissions originate from road freight transport. We examined the potential of all-electric freight trucks to achieve 64% GHG emissions reduction by 2040. The results suggest that even the stringent regulations on fuel efficiency of conventional trucks will fail to steadily decrease the emissions. More than 65% of freight trucks would have to run on all-electric powertrains which translates into 100% sector penetration as early as 2025. We assessed the available local energy resources for mass market penetration of all-electric trucks. The results suggest that every 1% of GHG emissions reduction from road freight transport would require 1.5-3.8% additional hydroelectric generation by 2040. Correspondingly, a 64% reduction requires 12-33 TWh of electricity. That is 2.5-6.5 times the projected generation of the B.C.'s largest hydroelectric project in decades (Site C). Hence, new policies are required to support diversified renewable electricity generation and low-carbon pathways. For example, carbon capture and sequestration coupled with provincial reserves of natural gas can enable low-carbon hydrogen production and decrease the electricity requirements for zero-emission vehicles in B.C.