Tunneling effect in antioxidant, prooxidant, and regeneration reactions of vitamin E

Nagaoka S; Inoue M; Nishioka C; Nishioku Y; Tsunoda S; Ohguchi C; Ohara K; Mukai K; Nagashima U

Journal of Physical Chemistry B, Vol.104, No.4, 856-862, 2000

Nagaoka S, Inoue M, Nishioka C, Nishioku Y, Tsunoda S, Ohguchi C, Ohara K, Mukai K, Nagashima U

Studies of the kinetics of the proton- or hydrogen-transfer reactions concerning vitamin E in solutions and in micellar dispersions by means of stopped-flow and absorption spectroscopy indicated that proton tunneling plays an important role in the antioxidant and regeneration reactions that are advantageous in vivo but not as a part of the harmful prooxidant action.

Keywords:PROTON-TRANSFER REACTION;LONG-LIVED RADICALS;METHYLLINOLEATE;ALPHA-TOCOPHEROL;ELECTRON;PEROXIDATION;UBIQUINONES;DERIVATIVES;INHIBITION;CHEMISTRY