Poly(methacrylic acid-co-2-aminoethyl methacrylate) (MAA-AMA) was simply synthesized by free radical polymerization. Immobilization of 2,4-dihydroxybenzaldehyde on MAA-AMA was done via Schiff base formation to obtain MAA-AMA(BZ). The qualitative and quantitative analyses of immobilization were done by nuclear magnetic resonance spectroscopy. The degree of immobilization of 2,4-dihydroxybenzaldehyde on MAA-AMA was 16-18%. Surface charge and particle size of MAA-AMA(BZ) is pH sensitive. In addition, intermolecular amidation provided cross-link structure at pH 12. The MAA-AMA(BZ) acted as an antifungal against Aspergillus genus with a percentage efficiency up to 25% against A. fumigatus.