A self-powered CH3NH3PbI3 photodetector (PD) based on ZnO microsphere (MS) array scaffold was reported. Through scanning electron microscopy images, a ZnO microsphere array consisted of nanosheets can be seen on ZnO mesh structure. Based on this novel structure, we first fabricated CH3NH3PbI3 photodetector with ZnO MS as the electron selective layer and MoO3 hole selective layer. Under light, the PDs showed the detection wavelength ranges from 300 to 800 nm, the responsivity values up to 48 mA/W, detectivity values as large as 4.5 x 10(11) Jones, on/off ratio up to 1400, and rise and fall time less than 14 ms, these results are comparable with the reported perovskite PDs. Furthermore, because of the effective absorption for ZnO microsphere in ultraviolet (UV) region, our device showed a significant UV detection performance. These results have great value on the scaffolds of perovskite materials for high performance devices. (C) 2018 Elsevier B.V. All rights reserved.