The effect of combining a thermodynamic promoter, tetrabutylammonium bromide (TBAB), with a kinetic promoter, sodium dodecyl sulphate (SDS), to a methane clathrate system was investigated. Kinetic growth experiments were conducted in a semi-batch stirred tank crystallizer at driving forces of 1500kPa using a range of 100 to 1500ppm SDS and 200 to 200000ppm TBAB. Solutions containing low concentrations of TBAB in water reduced methane hydrate growth rates up to 55% for 1250ppm TBAB compared to pure water. Solutions containing 900ppm SDS in water enhanced the growth rate by 880% compared to pure water. Solutions were then tested combining both promoters. The gradual addition of SDS from concentrations between 100 to 1250ppm to low-concentration TBAB systems between 200 to 1250ppm was initially found to reduce growth kinetics, but eventually increased the growth rates once a threshold SDS concentration was reached. In all cases, the promoting effect of the SDS was more pronounced in the absence of the TBAB. The growth kinetics of systems containing 5 and 20wt% TBAB also followed a similar inhibition-promotion trend with the SDS concentration. An increase of 177% in the gas consumption rate was observed when 1500ppm SDS was added to the 20wt% TBAB clathrate system. This work demonstrates that SDS can be added to a TBAB-water-methane system to enhance gas consumption rates, but care must be taken to ensure that the concentration of the additives places the system in a promotion regime.