Development and molecular engineering of new highly-efficient energetic biocidal materials is a significant challenge and of a great importance. Until now this type of materials included mostly halogen-rich nano-thermites and iodine-rich organic materials. So far, no energetic coordination polymers were reported as precursors for combustion-generated biocidal agents. Here, we demonstrate for the first time the synthesis of uniquely-structured three-dimensional energetic coordination polymer (ECP3) containing Zn metal centers and iodine- and nitrogen-rich bridging ligand (2). Upon its combustion, ECP3 is capable of generating gaseous reactive iodine species and elemental iodine-coated ZnO particles. ECP3 presents a novel approach for the design of efficient biocidal agents.