A new type of silica-organic hybrid nanoparticle (HNPs) (similar to)30nm in size, consisting of vinylsilylated silica nanoparticles (SNPs) of size similar to 2 nm and 1,6-hexanedithiol as the organic linker, were prepared by their interconnection via the thiol-ene reaction. The particle size of the HNPs varied depending on the concentration of the linker. Additionally, they could be dispersed in organic solvents and further successful chemical modification of the internal surfaces of HNPs indicated the accessibility of guest species into the internal nanospaces.