The EU is strongly committed to energy saving in buildings. Air leaks through the building envelope represent a significant percentage of buildings energy consumption. Locating and minimizing air leaks is thus necessary to optimize energy efficiency. This work presents the results of an experimental campaign that aimed to promote a discussion concerning the opportunities and constraints of using active IRT to detect air leakage points. The potential of active IRT was evaluated both in a qualitative approach, by comparing the thermograms with the ones obtained with passive IRT, and in a quantitative one, by testing methods of numerically interpret the thermograms. The results allowed concluding that active IRT increases the thermal contrast and the affected area, proving that active IRT combined with pressure differences is an effective methodology for detecting air infiltrations. In the quantitative approach different numerical methods can be used. Their selection depends on the aims of the study, as they can highlight different perspectives of the phenomenon. (C) 2018 Elsevier B.V. All rights reserved.