In this study, a series of thermo-responsive hydrogels based on N'N-dimethylaminoethyl methacrylate (DMAEM) and methacrylate functionalized poly(caprolactone) (PCL4-IEMA) were prepared by bulk photo-polymerization method. Poly(caprolactone) (PCL) was modified with 2-isocyanatoethylmethacrylate (IEMA) to form a macrocrosslinker due to its excellent biocompatibility to generate high-strength smart hydrogels with pH and temperature responsivity. The synthesized macro-crosslinker and PCL4-PDMAEM hydrogel were characterized by H-1 NMR, GPC and FT-IR analyses. Sol-gel transitions were examined by oscillatory measurements in Rheometer under UV light. Swelling kinetics as a function of time, swelling ratios at different pH values and temperatures were studied. pH responsive swelling behavior of PCL4-PDMEAM hydrogels was demonstrated with a highest swelling value at pH = 2. Temperature responsivity was also proved with a LCST around 40 degrees C between the shrunken and swollen state. Young modulus of the sample was also calculated around 0.3 MPa. The results indicated that using PCL4-IEMA as a macro-crosslinker is an effective way to obtain mechanically strong - tough hydrogels by means of dissipating the applied energy through flexible crosslink units. In addition, swelling and mechanical properties of the hydrogels could be tailored by varying the amount of the crosslinker.