화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Journal of Industrial and Engineering Chemistry, Vol.66, 196-202, October, 2018
DOI10.1016/j.jiec.2018.05.030  Export Citation
Preparation of antibacterial chitosan membranes containing silver nanoparticles for dental barrier membrane applications
Donghyun Lee, Sang Jin Lee1, Ji-Hoi Moon2, Joo Hyoung Kim3, Dong Nyoung Heo1, Jae Beum Bang4, Ho-Nam Lim1, and Il Keun Kwon1, †
  • Department of Dentistry Graduate School, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemun-gu, Seoul 02477, Republic of Korea
  • 1Department of Dental Materials, School of Dentistry, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemun-gu, Seoul 02477, Republic of Korea
  • 2Department of Maxillofacial Biomedical Engineering, School of Dentistry, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea
  • 3Department of Prosthodontics, School of Dentistry, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemun-gu, Seoul 02477, Republic of Korea
  • 4Department of Dental Education, School of Dentistry, Kyung Hee university, 26, Kyungheedae-ro, Dongdaemun-gu, Seoul 02477, Republic of Korea
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The materials of the dental barrier membranes (DBM), which is widely used for effective alveolar bone reconstruction, require high biocompatibility and additional functions. In this study, we prepared a chitosan/polyurethane (CSP) nanofibrous membrane incorporated silver nanoparticles (AgNPs) within the membrane. Characterization of CS-AgNP/polyurethane composite (AgCSP) nanofiber membranes showed that AgNPs were well embedded in chitosan membranes. In addition, biocompatibility and antibacterial effect against Porphyromonas gingivalis of the AgCSP was demonstrated by viability analysis and growth inhibition test. Collectively, AgCSP nanofiber membrane with antibacterial activity as well as biocompatibility may be useful in DBM and other tissue engineering applications.
Keywords:Chitosan nanofiber;Electrospinning;Silver nanoparticle;Antibacterial activity
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