화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Applied Chemistry for Engineering, Vol.29, No.5, 565-570, October, 2018
DOI10.14478/ace.2018.1055  Export Citation
초음파 추출공정을 이용한 닥나무로부터 항산화성분의 추출공정 최적화
Statistical Optimization of Antioxidant Extraction from Broussonetia kazinoki Using Ultrasound-assisted Extraction
이승범, 박보라, 유봉호1, †
  • 단국대학교 화학공학과
  • 1단국대학교 공과대학
Seung Bum Lee, Bo Ra Park, and Bong-Ho Yoo1, †
  • Department of Chemical Engineering, Dankook University, Gyeonggi 16890, Korea
  • 1College of Engineering, Dankook University, Gyeonggi 16890, Korea
E-mail:
초록
본 연구에서는 초음파 용매추출공정을 이용하여 닥나무로부터 항산화성분을 추출하고, 중심합성계획모델을 이용하여 추출공정을 최적화하였다. 중심합성계획모델의 반응치로는 추출수율과 DPPH 라디칼소거활성을 설정하고, 독립변수인 추출시간, 주정/초순수 부피비, 초음파 조사세기에 따른 주효과도와 교호효과도를 해석하였다. 추출수율과 DPPH 라디칼소거활성 모두 계량인자의 주효과도와 교호효과도를 모두 고려하였을 때 가장 큰 영향을 미치는 인자는 주정/초순수 부피비이었다. 반응표면분석법을 이용하여 추출공정의 최적화과정을 수행한 결과 최적추출조건은 추출시간 (19.92 min), 주정/초순수 부피비(54.23 vol%), 초음파 조사세기(557.65 W)로 나타났다. 이 조건으로부터 예상되는 반응치의 값은 추출수율(38.93 wt%), DPPH 라디칼소거활성(55.33%)으로 나타났다.
In this study, the antioxidant was extracted from Broussonetia kazinokii using ultrasound-assisted extraction (UAE) and optimized by using a response surface methodology. The response value of the central composite design model establishes the extraction yield and the DPPH radical scavenging activity. The extraction time and temperature and volume ratio of ethanol/ ultrapure water were selected as quantitative factors. When considering both the main and interaction effects, the factor having the greatest influence on the extraction yield and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity was the volume ratio of ethanol/ultrapure water. The results of optimal extraction conditions were the extraction time (19.92 min), volume ratio of ethanol/ultrapure water (54.23%), and ultrasonic irradiation power (557.65 W). We could also obtained expected results of the yield = 38.93 wt% and DPPH radical scavenging activity = 55.33% under these conditions.
Keywords:antioxidant;Broussonetia kazinokii;central composite design model;ultrasound-assisted extraction (UAE)
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