This paper addresses the dissipative control problem for nonlinear Markovian jump systems subject to actuator failures and mixed time-delays, where the mixed time-delays consist of both discrete and distributed time-delays and are mode-dependent. The purpose of the problem under investigation is to design a state feedback controller such that, in the presence of actuator failures and mixed time delays, the closed-loop system is asymptotically stable in the mean square sense while achieving the pre-specified dissipativity. By constructing a Lyapunov-Krasovskii functional and using a completing square approach, sufficient conditions are proposed for the existence of the desired controller in terms of the solvability of certain Hamilton-Jacobi inequalities. Finally, an illustrative numerical example is provided to demonstrate the effectiveness of the developed control scheme. (C) 2018 Elsevier Ltd. All rights reserved.