In this article, new vapor-liquid equilibrium data of the (ethane + R1234ze(E)) binary system are presented. The measurements are performed at six isotherms ranging from 272.27 to 347.52 K and for pressures of up to 4.89 MPa. The experiments were conducted by means of a static-analytic apparatus with phase analysis via gas chromatography, with resulting uncertainties of 0.03 K for temperature, 0.4 kPa for pressure, and 0.0043 for vapor and liquid mole fractions. The experimental data were correlated with the Peng-Robinson equation of state using the classical van der Waals mixing rules. For the three temperatures above the critical temperature of pure ethane, the critical compositions and pressures of the binary mixtures were also calculated on the basis of the extended asymptotic behavior laws. The results obtained show good agreement between experimental measurements and modeling, with a maximal deviation of 1.13% for bubble pressures and 1.23% for vapor molar fractions.