In the present work, rare earth element cerium doped zinc oxide and reduced graphene oxide containing nanocomposite (Ce-ZnO/rGO) modified glassy carbon electrode has been constructed for the determination of carbamazepine. The surface morphologies of the nanocomposite were characterized by Field Emission Scanning Electron Microscopy, X-Ray Diffraction and Fourier Transformed Infrared Spectrum techniques. The electrochemical properties are evaluated by the Cyclic Voltammetry (CV), Differential Pulse Voltammetry (DPV) and Electrochemical Impedance Spectroscopy (EIS). The modified electrode exhibited an excellent electrooxidation response towards the detection of carbamazepine at a lower oxidation potential (0.72 V). Under the optimal conditions, the oxidation peak current of carbamazepine showed a linear relationship with concentration over the range from 0.05 to 100 mu M with detection limit 1.2 nM. The sensitivity was found to be 0.086 mu A nM(-1) cm(-2). Furthermore the modified electrode displayed good reproducibility (RSD = 0.34%) and long-term stability (97.4%), as well as high selectivity. Finally, the proposed electrode was successfully applied to the direct determination of carbamazepine in practical samples (pharmaceutical tablet and urine sample) using standard addition method and gave satisfactory results ( > 98.7%).