Hydrogen production with high efficiency is a crucial issue for prospective hydrogen economy and carbon emission reduction. Methanol partial oxidation triggered over an h-BN-Pt/Al2O3 catalyst from a cold start in a Swiss-roll reactor with heat recirculation are investigated experimentally. The effects of methanol flow rate (0.5 and 0.6 mL min(-1)), O-2 concentration (21-35 vol%), and O-2-to-methanol (O-2/M) molar ratio (1.0-3.0) on the performance of methanol partial oxidation are examined. Heat exchange by transferring the excess enthalpy in the product gas to the feed gas is achieved in the reactor where the temperature of the feed gas before entering the catalyst bed can be promoted to around 100 degrees C. The experimental results indicate that a methanol flow rate of 0.5 mL min(-1) leads to more H-2 production compared to those obtained with a flow rate of 0.6 mL min(-1). In the conducted Swiss-roll reactor, oxygen supply plays an important role in accomplishing the partial oxidation, and the O-2/M ratio should be controlled beyond 1.0. By increasing the O-2 concentration, the H-2 concentration at O-2/M = 1.5 increases from 18.5 to 21.8%. However, the H-2 yield decreases, resulting from progressively dominant combustion mechanism. At a fixed gas hourly space velocity of 10,000 h(-1), the optimal O-2/M ratio for H-2 production is 2.5, for which the H-2 concentration and H-2 yield are 23.5% and 1.93 mol (mol methanol)(-1), respectively. The highest H-2 yield is close to the theoretical result. Overall, methanol partial oxidation along with heat recirculation in the Swiss-roll reactor can efficiently produce H-2, and the excess enthalpy recovery in the reactor can improve energy utilization.