Graphene oxide (GO)/Fe2O3 nanoplates supported N catalyst (Pt/GOFe) for room-temperature oxidation of formaldehyde (HCHO) was obtained via hydrothermal synthesis of Fe2O3 nanoplates, impregnation of GO and Pt precursor and NaBH4 reduction processes. Compared with TiO2 supported Pt (Pt/TiO2), Fe2O3 nanoplates supported Pt(Pt/Fe) and GO/commercial Fe2O3 supported Pt (Pt/GOFe-c), Pt/GOFe exhibited much higher catalytic activity toward room-temperature HCHO oxidation. The superior catalytic performance of Pt/GOFe is attributed to the unique morphology of Fe2O3 nanoplates, abundance of oxygen functionalities and the mobility of pi-pi bonds of GO, as well as plenty of active oxygen species resulted from the interaction between Pt and GO/ Fe2O3 . The in-situ DRIFTS results revealed that the surface hydroxyls played an important role in HCHO oxidation reaction, and formate/DOM species were the main intermediates. The excellent catalytic performance and recyclability make Pt/GOFe an efficient catalyst for HCHO oxidation at room temperature, which sheds a new light on rational design and fabrication of advanced catalyst for indoor air purification.