Equilibrium batch and dynamic column adsorption of bioethanol from the liquid phase on a commercial activated carbon was investigated. The effects of operational parameters, including flow rate, bed height, and initial solute concentration on the column breakthrough curve were studied. Axial dispersion was estimated by a tracer experimental breakthrough curve. Two mathematical models were developed to predict dynamic experimental results. The equilibrium results showed that the Toth isotherm could better predict the experimental adsorption data than the Langmuir model. The dynamic experimental results showed that increasing the flow rate decreases the column capacity. The macropore diffusion model and the linear driving force model were in good agreement with the experimental dynamic results.