The probability of successful tests in microdroplet tests is relatively low because of its high fiber failure rate caused by oversize embedded fiber length. Meanwhile, the scattering of the IFSS calculated by the maximum pull-out force is always high due to sensitive to the microscopic geometrical and experimental parameters. Hence, a set of suitable microscopic parameters are essencial but always determined by trial and error. In this paper, a virtual testing method on microdroplet test is introduced to simulate the test process and determine the appropriate test parameters, so as to increase the success rate and efficiency for actual test. Accurate response-displacement curve and IFSS are obtained and compared with those from actual test. Then we use this virtual experimental method to complete a sensitivity analysis of the experimental parameters. Finally, considering thermal residual stress and the interface debonding slip, the interface failure process and the stress transfer mechanism are discussed in detail and the damage propagation processes of the tough and brittle interfaces are described. Apart from guiding actual test, this virtual experiment method can be used for any single-filament-composite test and provide more detailed material information than actual experiments as well as a direct reference for optimum design. [GRAPHICS]