A novel platinum-palladium/carbon nanowires (PtPd/CNWs) catalysts are successfully prepared by electrospinning for the oxygen reduction reaction (ORR). The prepared PtPd/CNWs catalysts exist in the form of membrane, which can be directly applied as catalyst layer in membrane electrode assembly. The ORR activity of binary PtPd/CNWs catalysts are enhanced significantly in comparison to the ternary platinum-palladium-gold/carbon nanowires (PtPdAu/CNWs) catalysts and 20% Pt/C. Here, the gold in PtPdAu/CNWs mainly exists in larger gold nanoparticles rather than in the form of ternary alloy with Pt, Pd. The mass activity and special activity of PtPd/CNWs are 4.230 times and 4.225 times than that of 20% Pt/C, respectively. Moreover, the electrochemical active surface areas (ECSAs) of PtPd/CNWs catalysts almost keep constant after 5000 potential cycling, whereas 20% Pt/C drops almost 40% after 5000 potential cycling. (C) 2018 Hydrogen Energy Publications LLC. Published by Elsevier Ltd. All rights reserved.