In this work, we demonstrated a organic/inorganichybrid blue-light-emitting diodes (LEDs) device, where nanostructured ZnSe/ZnS multilayer films were used as light-emitting layer and poly(3,4-ethylene-dioxythiophene)-poly(styrene-sulfonate) acted as hole injection layer. Both intense blue photoluminescence and electroluminescence emission of this device were observed. The turn-on voltage of the blue LEDs was about 14V with the forward voltage. The current density reached around 2000mA/cm(2) when the forward voltage was 21V. In addition, the electroluminescence mechanism of this structure was analyzed in detail. These results offered a new idea in the field of blue LEDs. Meanwhile, blue LEDs with perfect performance are good for the realization of full-color displays and white LEDs.