Some manufacturing processes of polymeric materials, such as injection molding or film blowing, cause the final product to be highly anisotropic. In this study, the mechanical behavior of drawn polyethylene (PE) tapes is investigated via micromechanical modeling. An elasto-viscoplastic micromechanical model, developed within the framework of the so-called composite inclusion model, is presented to capture the anisotropic behavior of oriented semicrystalline PE. Two different phases, namely amorphous and crystalline (both described by elasto-viscoplastic constitutive models), are considered at the microstructural level. The initial oriented crystallographic structure of the drawn tapes is taken into account. It was previously shown by Sedighiamiri et al. (Comp. Mater. Sci. 2014, 82, 415) that by only considering the oriented crystallographic structure, it is not possible to capture the macroscopic anisotropic behavior of drawn tapes. The main contribution of this study is the development of an anisotropic model for the amorphous phase within the micromechanical framework. An Eindhoven glassy polymer (EGP)-based model including different sources of anisotropy, namely anisotropic elasticity, internal stress in the elastic network and anisotropic viscoplasticity, is developed for the amorphous phase and incorporated into the micromechanical model. Comparisons against experimental results reveal remarkable improvements of the model predictions (compared to micromechanical model predictions including isotropic amorphous domains) and thus the significance of the amorphous phase anisotropy on the overall behavior of drawn PE tapes. (c) 2019 The Authors. Journal of Polymer Science Part B: Polymer Physics published by Wiley Periodicals, Inc. J. Polym. Sci., Part B: Polym. Phys. 2019, 57, 378-391