The development of devices capable of generating energy through biofluids, such as sweat, is an effort to integrate flexible devices that can be powered and used on the skin. A patch-type completely enzymatic biofuel cell (p-EBFC) is developed using bilirubin oxidase- and lactate oxidase-based electrodes as biocathode and bioanode respectively, where both enzymes are immobilized on flexible Toray carbon paper-modified. The evaluation of the half-cells shows that the bioelectrodes had good catalytic activity towards the oxygen reduction and lactic acid oxidation reactions using natural human sweat. The wireless p-EBFC on the skin is capable to delivery an open circuit voltage of 0.55 +/- 0.03 V and a short circuit current of 140 +/- 4 mu A cm(-2). Also, the p-EBFC maintains its performance of 20 mu W cm(-2) and 30 mu A cm(-2) continuously for 30 min in a sweat delivery from the arm of a healthy volunteer during workouts. In addition, a wireless device is incorporated in order to monitor via a cell phone the energy produced in real time.