The "shuttle effect" of polysulfides and sluggish kinetics of sulfur redox are main problems in Lithium-Sulfur batteries. As a result, the Lithium-Sulfur battery systems are still far from commercialization for practical utilities. In this work, we design and prepare a Lanthanum lithium oxide-based multi-functional interlayer with good electronic and lithium ion conduction as well as efficient for polysulfide blocking. We obtain the multi-functional interlayer combined cathode by coating a composite of Lanthanum lithium oxide on as-prepared sulfur electrode. The modified sulfur cathode with such interlayer configuration gives enhanced electrochemical performance (1458.00 mA h g(-1) capacity at initial cycle and 1004.40 mA h g(-1) during the first cycle with 1C rate) with outstanding cycling stability up to 250th cycle delivering the corresponding discharge capacity of 872.79 mA h g(-1) in Li-S batteries. And, the rate performance has been improved by the facile strategy. (C) The Author(s) 2019. Published by ECS.