Poly(2-aminothiophenol) (PATH) was prepared by oxidative chemical polymerization of 2-aminothiophenol in aqueous HCl medium using ammonium persulfate as oxidant. The obtained polymer sample was characterized using different techniques. The kinetics of polymerization reaction were investigated. The data show that both initial and overall reaction rates increase with increasing monomer, oxidant and HCl concentrations. Also both initial and overall polymerization reaction rates increase with increasing temperature. The nanostructure of the prepared PATH was fabricated with silver nanoparticles. The antibacterial activity of the synthesized polymer and its nanostructure with silver nanoparticles was studied against sulfate-reducing bacteria. The synthesized polymer and its nanostructure showed good antibacterial activity.